Changes in Cerebral Arteries and Parenchymal Arterioles With Aging
نویسندگان
چکیده
منابع مشابه
Aging is associated with changes to the biomechanical properties of the posterior cerebral artery and parenchymal arterioles.
Artery remodeling, described as a change in artery structure, may be responsible for the increased risk of cardiovascular disease with aging. Although the risk for stroke is known to increase with age, relatively young animals have been used in most stroke studies. Therefore, more information is needed on how aging alters the biomechanical properties of cerebral arteries. Posterior cerebral art...
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چکیده ندارد.
15 صفحه اولIncreased pressure-induced tone in rat parenchymal arterioles vs. middle cerebral arteries: role of ion channels and calcium sensitivity.
Brain parenchymal arterioles (PAs) are high-resistance vessels that branch off pial arteries and perfuse the brain parenchyma. PAs are the target of cerebral small vessel disease and have been shown to have greater pressure-induced tone at lower pressures than pial arteries. We investigated mechanisms by which brain PAs have increased myogenic tone compared with middle cerebral arteries (MCAs),...
متن کاملEffects of luminal shear stress on cerebral arteries and arterioles.
The effect of luminal shear stress was studied in cerebral arteries and arterioles. Middle cerebral arteries (MCA) and penetrating arterioles (PA) were isolated from male Long-Evans rats, mounted in a tissue bath, and pressurized. After the development of spontaneous tone, inside diameters were 186 +/- 5 microm (n = 28) for MCA and 65 +/- 3 microm (n = 37) for PA. MCA and PA constricted approxi...
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BACKGROUND AND PURPOSE We used quantitative diffusion MR imaging to investigate the microstructural changes that occur in white matter during normal aging in order to identify regional changes in anisotropy and to quantify global microstructural changes by use of whole-brain diffusion histograms. METHODS Full diffusion tensor MR imaging was performed in 20 healthy volunteers, 20 to 91 years o...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2018
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.118.10865